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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Heat shock protein HSP 90-beta | ||
| Ligand | BDBM50013705 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1349362 (CHEMBL3269585) | ||
| IC50 | 310000±n/a nM | ||
| Citation |  Bhat, R; Adam, AT; Lee, JJ; Gasiewicz, TA; Henry, EC; Rotella, DP Towards the discovery of drug-like epigallocatechin gallate analogs as Hsp90 inhibitors. Bioorg Med Chem Lett24:2263-6 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Heat shock protein HSP 90-beta | |||
| Name: | Heat shock protein HSP 90-beta | ||
| Synonyms: | HS90B_HUMAN | HSP 84 | HSP 90 | HSP90AB1 | HSP90B | HSPC2 | HSPCB | Heat Shock Protein 90 (Hsp90) | Heat shock protein HSP 90 (Hsp90) | ||
| Type: | Molecular Chaperone | ||
| Mol. Mass.: | 83229.45 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08238 | ||
| Residue: | 724 | ||
| Sequence: |
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| BDBM50013705 | |||
| n/a | |||
| Name | BDBM50013705 | ||
| Synonyms: | CHEMBL3264538 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H24O8 | ||
| Mol. Mass. | 416.4212 | ||
| SMILES | O[C@H]1CC[C@H](CC1)C(=O)O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 |r,wU:4.7,1.0,wD:21.24,10.10,(52.18,-55.64,;50.85,-54.87,;49.51,-55.64,;48.18,-54.86,;48.19,-53.33,;49.52,-52.56,;50.85,-53.32,;46.86,-52.55,;45.52,-53.32,;46.86,-51.01,;45.53,-50.24,;44.18,-51.01,;42.85,-50.23,;41.52,-51,;41.52,-52.54,;40.18,-50.23,;40.18,-48.69,;38.85,-47.92,;41.51,-47.92,;42.85,-48.68,;44.19,-47.9,;45.53,-48.68,;46.87,-47.92,;48.2,-48.7,;49.53,-47.93,;49.54,-46.39,;50.87,-45.62,;48.2,-45.62,;48.2,-44.08,;46.87,-46.39,)| | ||
| Structure | 
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