| Reaction Details |
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 | Report a problem with these data |
| Target | Interferon alpha/beta receptor 1 |
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| Ligand | BDBM50014088 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1350279 (CHEMBL3267262) |
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| Kd | 4000±n/a nM |
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| Citation |  Guo, W; Wisniewski, JA; Ji, H Hot spot-based design of small-molecule inhibitors for protein-protein interactions. Bioorg Med Chem Lett24:2546-54 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interferon alpha/beta receptor 1 |
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| Name: | Interferon alpha/beta receptor 1 |
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| Synonyms: | CRF2-1 | Cytokine receptor class-II member 1 | Cytokine receptor family 2 member 1 | IFN-R-1 | IFN-alpha/beta receptor 1 | IFNAR | IFNAR1 | INAR1_HUMAN | Type I interferon receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63519.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_106149 |
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| Residue: | 557 |
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| Sequence: | MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVT
FSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF
TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERI
ENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ
NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK
GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP
VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSV
FSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE
YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSN
EDESESKTSEELQQDFV
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| BDBM50014088 |
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| n/a |
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| Name | BDBM50014088 |
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| Synonyms: | CHEMBL1617534 | DNDI1417107 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17NS |
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| Mol. Mass. | 279.399 |
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| SMILES | CNCc1ccccc1Sc1cccc2ccccc12 |
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| Structure | 
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