Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50018999 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1365290 (CHEMBL3292384) |
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Ki | 32±n/a nM |
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Citation | Nagase, H; Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Nemoto, T; Gouda, H; Hirono, S; Fujii, H Design and synthesis of quinolinopropellane derivatives with selectived opioid receptor agonism. Bioorg Med Chem Lett24:2851-4 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50018999 |
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n/a |
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Name | BDBM50018999 |
Synonyms: | CHEMBL3287469 |
Type | Small organic molecule |
Emp. Form. | C30H28N2O |
Mol. Mass. | 432.5561 |
SMILES | Oc1ccc2C[C@@]34CN(Cc5ccccc5)CC[C@@]3(Cc3nc5ccccc5cc3C4)c2c1 |r| |
Structure |
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