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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neurotensin receptor type 2 | ||
| Ligand | BDBM82417 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1364514 (CHEMBL3295311) | ||
| EC50 | 217±n/a nM | ||
| Citation |  Thomas, JB; Giddings, AM; Wiethe, RW; Olepu, S; Warner, KR; Sarret, P; Gendron, L; Longpre, JM; Zhang, Y; Runyon, SP; Gilmour, BP Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound. J Med Chem57:5318-32 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neurotensin receptor type 2 | |||
| Name: | Neurotensin receptor type 2 | ||
| Synonyms: | High-affinity levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2_RAT | Neurotensin receptor 2 | Neurotensin receptor type 2 | Ntr2 | Ntsr2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 46280.50 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1466615 | ||
| Residue: | 416 | ||
| Sequence: |
| ||
| BDBM82417 | |||
| n/a | |||
| Name | BDBM82417 | ||
| Synonyms: | CHEMBL461604 | SR 48527 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H29ClN4O5 | ||
| Mol. Mass. | 549.017 | ||
| SMILES | COc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)N[C@@H](C1CCCCC1)C(O)=O |wD:29.32,(4.51,5.44,;5.54,4.29,;5.06,2.83,;3.56,2.51,;3.08,1.04,;4.11,-.1,;5.62,.22,;6.65,-.93,;6.17,-2.39,;6.09,1.68,;7.6,2,;8.08,.54,;9.62,.54,;10.09,2,;8.85,2.91,;8.85,4.45,;7.51,5.22,;7.51,6.76,;8.85,7.53,;10.18,6.76,;11.56,7.58,;12.95,6.79,;14.28,7.57,;12.95,5.19,;11.56,4.39,;10.18,5.22,;10.52,-.71,;12.05,-.55,;9.89,-2.11,;10.8,-3.36,;10.17,-4.77,;8.64,-4.93,;8.01,-6.34,;8.92,-7.58,;10.45,-7.42,;11.08,-6.01,;12.33,-3.2,;13.24,-4.45,;12.96,-1.79,)| | ||
| Structure | 
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