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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Delta-type opioid receptor | ||
| Ligand | BDBM50020711 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1363047 (CHEMBL3293116) | ||
| Ki | 0.490000±n/a nM | ||
| Citation |  Schoultz, BW; Hjørnevik, T; Reed, BJ; Marton, J; Coello, CS; Willoch, F; Henriksen, G Synthesis and evaluation of three structurally related¹8F-labeled orvinols of different intrinsic activities: 6-O-[¹8F]fluoroethyl-diprenorphine ([¹8F]FDPN), 6-O-[¹8F]fluoroethyl-buprenorphine ([¹8F]FBPN), and 6-O-[¹8F]fluoroethyl-phenethyl-orvinol ([¹8F]FPEO). J Med Chem57:5464-9 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Delta-type opioid receptor | |||
| Name: | Delta-type opioid receptor | ||
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40382.98 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. | ||
| Residue: | 372 | ||
| Sequence: |
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| BDBM50020711 | |||
| n/a | |||
| Name | BDBM50020711 | ||
| Synonyms: | CHEMBL3291216 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H36FNO4 | ||
| Mol. Mass. | 505.6202 | ||
| SMILES | [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@@]2(OCCF)C=C1)ccc3O |r,wU:13.12,29.34,1.0,18.22,16.19,wD:7.7,14.40,c:39,THB:10:9:14:4.5.6,(38.27,-13.82,;38.28,-12.11,;36.7,-13.02,;35.26,-12.11,;36.01,-10.81,;35.26,-9.49,;36.01,-8.17,;37.49,-8.17,;38.81,-7.4,;37.53,-6.64,;38.3,-5.29,;36.75,-7.61,;36.75,-9.48,;37.53,-10.81,;38.3,-9.49,;39.83,-9.49,;40.59,-10.82,;40.99,-9.32,;42.14,-10.83,;42.92,-9.49,;42.9,-12.17,;43.68,-10.83,;44.45,-9.49,;46,-9.48,;46.77,-10.83,;48.31,-10.82,;49.08,-9.48,;48.3,-8.14,;46.76,-8.15,;39.81,-12.14,;40.57,-13.47,;39.79,-14.81,;40.55,-16.15,;39.76,-17.49,;39.79,-10.63,;38.3,-11.04,;33.73,-9.49,;32.96,-10.81,;33.73,-12.11,;32.95,-13.46,)| | ||
| Structure | 
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