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TargetSerine/threonine-protein kinase 17B
LigandBDBM50024271
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1435934 (CHEMBL3382244)
Kd 660±n/a nM
Citation Gao, LJKovackova, SSála, MRamadori, ATDe Jonghe, SHerdewijn, P Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach. J Med Chem57:7624-43 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serine/threonine-protein kinase 17B
Name:Serine/threonine-protein kinase 17B
Synonyms:DRAK2 | ST17B_HUMAN | STK17B | Serine/threonine-protein kinase 17B | Serine/threonine-protein kinase 17B (STK17B)
Type:Enzyme
Mol. Mass.:42332.49
Organism:Homo sapiens (Human)
Description:O94768
Residue:372
Sequence:
MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
PNPHELVSDLLC
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  Blast E-value cutoff:
BDBM50024271
n/a
NameBDBM50024271
Synonyms:CHEMBL3334946
TypeSmall organic molecule
Emp. Form.C20H22N4O2S
Mol. Mass.382.479
SMILESCOc1cc(ccc1N)-c1cnc2snc(NC(=O)C3CCCCC3)c2c1
Structure
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