| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17A |
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| Ligand | BDBM50024284 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1435938 (CHEMBL3382248) |
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| IC50 | 560±n/a nM |
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| Citation |  Gao, LJ; Kovackova, S; Sála, M; Ramadori, AT; De Jonghe, S; Herdewijn, P Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach. J Med Chem57:7624-43 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 17A |
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| Name: | Serine/threonine-protein kinase 17A |
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| Synonyms: | DRAK1 | ST17A_HUMAN | STK17A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46544.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_109255245 |
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| Residue: | 414 |
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| Sequence: | MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYS
LCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPW
VINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTR
DVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPI
SMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRT
LLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSE
TKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
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| BDBM50024284 |
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| n/a |
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| Name | BDBM50024284 |
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| Synonyms: | CHEMBL3334979 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N2O3S |
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| Mol. Mass. | 396.503 |
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| SMILES | COc1ccc(cc1OC)-c1cnc2scc(NC(=O)C3CCCCC3)c2c1 |
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| Structure | 
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