| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-tyrosine kinase 6 |
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| Ligand | BDBM50026032 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1438913 (CHEMBL3381838) |
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| IC50 | 1300±n/a nM |
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| Citation |  Shim, HJ; Yang, HR; Kim, HIe; Kang, SA; No, KT; Jung, YH; Lee, ST Discovery of (E)-5-(benzylideneamino)-1H-benzo[d]imidazol-2(3H)-one derivatives as inhibitors for PTK6. Bioorg Med Chem Lett24:4659-63 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-tyrosine kinase 6 |
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| Name: | Protein-tyrosine kinase 6 |
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| Synonyms: | BRK | Breast tumor kinase | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | PTK6 | PTK6_HUMAN | Protein-tyrosine kinase 6 (BRK) | Tyrosine Kinase BRK | Tyrosine-protein kinase 6 | Tyrosine-protein kinase BRK |
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| Type: | Tyrosine-protein kinase |
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| Mol. Mass.: | 51839.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 451 |
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| Sequence: | MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQG
YVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRD
TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPH
WDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMK
KLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGM
CYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALS
RGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLM
LTCWCRDPEQRPCFKALRERLSSFTSYENPT
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| BDBM50026032 |
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| n/a |
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| Name | BDBM50026032 |
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| Synonyms: | CHEMBL3335251 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10Br2N2O2S |
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| Mol. Mass. | 442.125 |
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| SMILES | COc1cc(Br)c(Br)c(\C=N\c2ccc3scnc3c2)c1O |
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| Structure | 
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