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Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50030076 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1438384 (CHEMBL3383059) | ||
| Ki | 1394±n/a nM | ||
| Citation |  Lucchesi, V; Hurst, DP; Shore, DM; Bertini, S; Ehrmann, BM; Allarà, M; Lawrence, L; Ligresti, A; Minutolo, F; Saccomanni, G; Sharir, H; Macchia, M; Di Marzo, V; Abood, ME; Reggio, PH; Manera, C CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. J Med Chem57:8777-91 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
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| BDBM50030076 | |||
| n/a | |||
| Name | BDBM50030076 | ||
| Synonyms: | CHEMBL3353433 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H23N3O4 | ||
| Mol. Mass. | 357.4036 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cc2cccnc2n(CCC(O)=O)c1=O |(38.26,1.98,;36.93,1.2,;36.93,-.34,;35.6,-1.12,;34.26,-.34,;34.25,1.19,;35.59,1.97,;32.93,-1.12,;31.6,-.36,;31.59,1.19,;30.27,-1.14,;28.93,-.38,;27.6,-1.15,;26.27,-.39,;24.94,-1.16,;24.94,-2.7,;26.27,-3.47,;27.61,-2.7,;28.94,-3.46,;28.94,-5,;30.28,-5.77,;30.28,-7.31,;28.95,-8.09,;31.62,-8.08,;30.28,-2.69,;31.61,-3.45,)| | ||
| Structure | 
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