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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Genome polyprotein | ||
| Ligand | BDBM50030459 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1434210 (CHEMBL3384588) | ||
| Ki | 130±n/a nM | ||
| Citation |  Bhakat, S; Karubiu, W; Jayaprakash, V; Soliman, ME A perspective on targeting non-structural proteins to combat neglected tropical diseases: Dengue, West Nile and Chikungunya viruses. Eur J Med Chem87:677-702 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Genome polyprotein | |||
| Name: | Genome polyprotein | ||
| Synonyms: | POLG_WNV | polyprotein precursor | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 380170.63 | ||
| Organism: | West Nile virus | ||
| Description: | ChEMBL_1438217 | ||
| Residue: | 3430 | ||
| Sequence: |
| ||
| BDBM50030459 | |||
| n/a | |||
| Name | BDBM50030459 | ||
| Synonyms: | CHEMBL3344321 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H46Cl2N8O3 | ||
| Mol. Mass. | 613.623 | ||
| SMILES | NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)Cc1ccc(Cl)c(Cl)c1)C(=O)NC[C@H]1CC[C@@H](CC1)NC(N)=N |r,wU:34.38,9.9,wD:31.31,5.4,(16.97,-13.05,;16.9,-11.52,;15.54,-10.81,;15.47,-9.27,;14.11,-8.56,;14.04,-7.02,;12.68,-6.3,;11.38,-7.13,;11.44,-8.67,;10.01,-6.42,;9.94,-4.88,;11.24,-4.05,;11.18,-2.52,;12.48,-1.69,;12.42,-.15,;8.71,-7.24,;7.38,-6.48,;7.37,-4.94,;6.05,-7.25,;4.72,-6.48,;4.71,-4.94,;3.38,-4.17,;2.05,-4.94,;.72,-4.17,;2.05,-6.48,;.72,-7.25,;3.38,-7.25,;15.34,-6.19,;15.28,-4.65,;16.7,-6.9,;18.02,-6.09,;19.38,-6.82,;19.42,-8.36,;20.78,-9.09,;22.1,-8.27,;22.05,-6.73,;20.68,-6,;23.46,-9,;24.77,-8.18,;24.72,-6.65,;26.13,-8.91,)| | ||
| Structure | 
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