| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group I member 3 |
|---|
| Ligand | BDBM50030476 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1434936 (CHEMBL3385873) |
|---|
| EC50 | 75±n/a nM |
|---|
| Citation |  Gege, C; Schlüter, T; Hoffmann, T Identification of the first inverse agonist of retinoid-related orphan receptor (ROR) with dual selectivity for RORß and ROR¿t. Bioorg Med Chem Lett24:5265-7 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nuclear receptor subfamily 1 group I member 3 |
|---|
| Name: | Nuclear receptor subfamily 1 group I member 3 |
|---|
| Synonyms: | CAR | NR1I3 | NR1I3_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39953.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1434936 |
|---|
| Residue: | 352 |
|---|
| Sequence: | MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
|
|
|
|---|
| BDBM50030476 |
|---|
| n/a |
|---|
| Name | BDBM50030476 |
|---|
| Synonyms: | CHEMBL458603 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H12Cl3N3OS |
|---|
| Mol. Mass. | 436.742 |
|---|
| SMILES | Clc1ccc(cc1)-c1nc2sccn2c1\C=N\OCc1ccc(Cl)c(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
