| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-6 |
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| Ligand | BDBM50031595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1441662 (CHEMBL3377639) |
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| IC50 | 28500±n/a nM |
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| Citation |  Limpachayaporn, P; Wagner, S; Kopka, K; Schober, O; Schäfers, M; Haufe, G Synthesis of 7-halogenated isatin sulfonamides: nonradioactive counterparts of caspase-3/-7 inhibitor-based potential radiopharmaceuticals for molecular imaging of apoptosis. J Med Chem57:9383-95 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-6 |
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| Name: | Caspase-6 |
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| Synonyms: | Apoptotic protease Mch-2 | CASP-6 | CASP6 | CASP6_HUMAN | Caspase | MCH2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 33312.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55212 |
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| Residue: | 293 |
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| Sequence: | MSSASGLRRGHPAGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLT
LPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLS
HGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDN
QTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYG
SSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKSN
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| BDBM50031595 |
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| n/a |
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| Name | BDBM50031595 |
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| Synonyms: | CHEMBL3359187 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20FIN2O5S |
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| Mol. Mass. | 510.319 |
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| SMILES | COC[C@@H]1CCCN1S(=O)(=O)c1cc2C(=O)C(=O)N(CCCF)c2c(I)c1 |r| |
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| Structure | 
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