| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase Mu 2 |
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| Ligand | BDBM50038313 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1441153 (CHEMBL3378817) |
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| IC50 | 130±n/a nM |
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| Citation |  Rotili, D; De Luca, A; Tarantino, D; Pezzola, S; Forgione, M; Morozzo Della Rocca, B; Falconi, M; Mai, A; Caccuri, AM Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases. Eur J Med Chem89:156-71 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase Mu 2 |
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| Name: | Glutathione S-transferase Mu 2 |
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| Synonyms: | GST class-mu 2 | GST4 | GSTM2 | GSTM2-2 | GSTM2_HUMAN | Glutathione S-transferase Mu 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25743.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1441153 |
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| Residue: | 218 |
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| Sequence: | MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF
EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN
LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
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| BDBM50038313 |
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| n/a |
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| Name | BDBM50038313 |
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| Synonyms: | CHEMBL3360513 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10N4O5S |
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| Mol. Mass. | 346.318 |
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| SMILES | CONC(=O)c1ccc(Sc2ccc([N+]([O-])=O)c3nonc23)cc1 |
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| Structure | 
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