| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM50045438 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1459863 (CHEMBL3367286) |
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| IC50 | 5900±n/a nM |
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| Citation |  Raghav, N; Singh, M SAR studies of differently functionalized chalcones based hydrazones and their cyclized derivatives as inhibitors of mammalian cathepsin B and cathepsin H. Bioorg Med Chem22:4233-45 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 36777.57 |
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| Organism: | Capra hircus (Goat) |
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| Description: | n/a |
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| Residue: | 335 |
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| Sequence: | MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSW
NTDWGDKGFFKILRGQDHCGIESEIVAGMPCTHQY
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| BDBM50045438 |
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| n/a |
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| Name | BDBM50045438 |
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| Synonyms: | CHEMBL3309798 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N3O3 |
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| Mol. Mass. | 309.3193 |
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| SMILES | CC(=O)N1N=C(CC1c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |c:4| |
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| Structure | 
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