Reaction Details |
| Report a problem with these data |
Target | Cathepsin B |
---|
Ligand | BDBM50045446 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1459865 (CHEMBL3367288) |
---|
Ki | 3883±n/a nM |
---|
Citation | Raghav, N; Singh, M SAR studies of differently functionalized chalcones based hydrazones and their cyclized derivatives as inhibitors of mammalian cathepsin B and cathepsin H. Bioorg Med Chem22:4233-45 (2014) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Cathepsin B |
---|
Name: | Cathepsin B |
Synonyms: | n/a |
Type: | Protein |
Mol. Mass.: | 36777.57 |
Organism: | Capra hircus (Goat) |
Description: | n/a |
Residue: | 335 |
Sequence: | MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSW
NTDWGDKGFFKILRGQDHCGIESEIVAGMPCTHQY
|
|
|
BDBM50045446 |
---|
n/a |
---|
Name | BDBM50045446 |
Synonyms: | CHEMBL3309618 |
Type | Small organic molecule |
Emp. Form. | C21H17BrN2 |
Mol. Mass. | 377.277 |
SMILES | Brc1ccc(\C=C\C(=N/Nc2ccccc2)\c2ccccc2)cc1 |
Structure |
|