| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
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| Ligand | BDBM50045579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1453623 (CHEMBL3363472) |
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| IC50 | 225±n/a nM |
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| Citation |  Seerden, JP; Leusink-Ionescu, G; Woudenberg-Vrenken, T; Dros, B; Molema, G; Kamps, JA; Kellogg, RM Synthesis and structure-activity relationships of 4-fluorophenyl-imidazole p38a MAPK, CK1d and JAK2 kinase inhibitors. Bioorg Med Chem Lett24:3412-8 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform delta |
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| Name: | Casein kinase I isoform delta |
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| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47356.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48730 |
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| Residue: | 415 |
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| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
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| BDBM50045579 |
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| n/a |
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| Name | BDBM50045579 |
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| Synonyms: | CHEMBL3120985 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16FN6Na2O3P |
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| Mol. Mass. | 472.3204 |
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| SMILES | [Na+].[Na+].Cn1c(nc(c1-c1ccncc1)-c1ccc(F)cc1)-c1cn(CCP([O-])([O-])=O)nn1 |
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| Structure | 
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