| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Ligand | BDBM50046528 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1449353 (CHEMBL3372081) |
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| IC50 | 1940000±n/a nM |
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| Citation |  Srivilai, J; Khorana, N; Waranuch, N; Suphrom, N; Ingkaninan, K Conformational analysis of an anti-androgenic, (E,E)-8-hydroxygermacrene B, using NOESY and dynamic NMR spectroscopy. Bioorg Med Chem Lett24:3526-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Synonyms: | S5A1_RAT | Srd5a1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29788.29 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1441437 |
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| Residue: | 259 |
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| Sequence: | MVPLMELDELCLLDMLVYLEGFMAFVSIVGLRSVGSPYGRYSPQWPGIRVPARPAWFIQE
LPSMAWPLYEYIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLVTFVLA
FLFCTFNGYVQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGE
TGYKIPRGGLFEYVSAANYFGELVEWCGFALASWSLQGVVFALFTLSTLLTRAKQHHQWY
HEKFEDYPKSRKILIPFVL
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| BDBM50046528 |
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| n/a |
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| Name | BDBM50046528 |
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| Synonyms: | CHEMBL3309453 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22O |
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| Mol. Mass. | 218.3346 |
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| SMILES | [#6]\[#6](-[#6])=[#6]-1/[#6]\[#6]=[#6](-[#6])/[#6]-[#6]\[#6]=[#6](-[#6])/[#6]-[#6]-1=O |t:5,10| |
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| Structure | 
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