| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50046717 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1451901 (CHEMBL3363071) |
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| IC50 | 1580±n/a nM |
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| Citation |  Chen, H; Hao, L; Zhu, M; Yang, T; Wei, S; Qin, Z; Zhang, P; Li, X Synthesis of bi-/tricyclic azasugars fused thiazinan-4-one and their HIV-RT inhibitory activity. Bioorg Med Chem Lett24:3426-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50046717 |
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| n/a |
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| Name | BDBM50046717 |
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| Synonyms: | CHEMBL2018791 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13NO4S |
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| Mol. Mass. | 267.301 |
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| SMILES | [H][C@@]12Sc3ccccc3C(=O)N1C[C@@H](O)[C@H](O)[C@@H]2O |r| |
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| Structure | 
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