| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Papain |
|---|
| Ligand | BDBM50048079 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1453723 (CHEMBL3364438) |
|---|
| IC50 | 280±n/a nM |
|---|
| Citation |  Wammes, AE; Hendriks, TG; Amatdjais-Groenen, HI; Wijdeven, MA; van Hest, JC; van Delft, FL; Ritschel, T; Rutjes, FP Influence of azide incorporation on binding affinity by small papain inhibitors. Bioorg Med Chem22:5593-603 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Papain |
|---|
| Name: | Papain |
|---|
| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 38923.01 |
|---|
| Organism: | Carica papaya |
|---|
| Description: | Papain was purchased from Sigma, Germany. |
|---|
| Residue: | 345 |
|---|
| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
|
|
|
|---|
| BDBM50048079 |
|---|
| n/a |
|---|
| Name | BDBM50048079 |
|---|
| Synonyms: | CHEMBL3357955 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18N6O3 |
|---|
| Mol. Mass. | 378.3846 |
|---|
| SMILES | Oc1ccc(C[C@H](NC(=O)c2ccc(CN=[N+]=[N-])cc2)C(=O)NCC#N)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
