| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
|---|
| Ligand | BDBM50050893 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1459288 (CHEMBL3367518) |
|---|
| IC50 | 530±n/a nM |
|---|
| Citation |  Nakao, A; Suzuki, H; Ueno, H; Iwasaki, H; Setsuta, T Discovery of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. Bioorg Med Chem Lett24:4336-40 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosylhomocysteinase |
|---|
| Name: | Adenosylhomocysteinase |
|---|
| Synonyms: | AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47714.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507791 |
|---|
| Residue: | 432 |
|---|
| Sequence: | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
|
|
|
|---|
| BDBM50050893 |
|---|
| n/a |
|---|
| Name | BDBM50050893 |
|---|
| Synonyms: | CHEMBL3322532 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H34Cl2N4O3 |
|---|
| Mol. Mass. | 569.522 |
|---|
| SMILES | CN(Cc1ccccc1)C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
