| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50053409 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1460137 (CHEMBL3369122) |
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| Ki | 1.1±n/a nM |
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| Citation |  Salama, I; Löber, S; Hübner, H; Gmeiner, P Synthesis and binding profile of haloperidol-based bivalent ligands targeting dopamine D(2)-like receptors. Bioorg Med Chem Lett24:3753-6 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50053409 |
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| n/a |
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| Name | BDBM50053409 |
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| Synonyms: | CHEMBL3318846 |
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| Type | Small organic molecule |
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| Emp. Form. | C52H60Cl2F2N4O6 |
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| Mol. Mass. | 945.959 |
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| SMILES | Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCN1CCN(CCC(=O)OC2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1 |
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| Structure | 
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