| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase A1 |
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| Ligand | BDBM50054198 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1458318 (CHEMBL3369280) |
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| Ki | 360±n/a nM |
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| Citation |  Perperopoulou, FD; Tsoungas, PG; Thireou, TN; Rinotas, VE; Douni, EK; Eliopoulos, EE; Labrou, NE; Clonis, YD 2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1. Bioorg Med Chem22:3957-70 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase A1 |
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| Name: | Glutathione S-transferase A1 |
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| Synonyms: | GST class-alpha member 1 | GST-epsilon | GSTA1 | GSTA1-1 | GSTA1_HUMAN | GTH1 | Glutathione S-transferase (GST) | HA subunit 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 25636.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Glutathione-S-Transferase (GST, N-terminally) |
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| Residue: | 222 |
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| Sequence: | MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
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| BDBM50054198 |
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| n/a |
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| Name | BDBM50054198 |
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| Synonyms: | CHEMBL3310888 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9BrO3 |
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| Mol. Mass. | 293.113 |
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| SMILES | Oc1ccccc1C(=O)c1cc(Br)ccc1O |
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| Structure | 
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