| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
|---|
| Ligand | BDBM50056748 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1454104 (CHEMBL3362589) |
|---|
| IC50 | 6300±n/a nM |
|---|
| Citation |  Duan, YT; Sang, YL; Makawana, JA; Teraiya, SB; Yao, YF; Tang, DJ; Tao, XX; Zhu, HL Discovery and molecular modeling of novel 1-indolyl acetate--5-nitroimidazole targeting tubulin polymerization as antiproliferative agents. Eur J Med Chem85:341-51 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Similar to alpha-tubulin isoform 1 |
|---|
| Name: | Similar to alpha-tubulin isoform 1 |
|---|
| Synonyms: | Similar to alpha-tubulin isoform 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 10383.05 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_104716 |
|---|
| Residue: | 99 |
|---|
| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
|
|
|
|---|
| BDBM50056748 |
|---|
| n/a |
|---|
| Name | BDBM50056748 |
|---|
| Synonyms: | CHEMBL3331002 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H17N5O6 |
|---|
| Mol. Mass. | 447.4003 |
|---|
| SMILES | [O-][N+](=O)c1cnc(\C=C/c2ccccc2[N+]([O-])=O)n1CCOC(=O)c1c[nH]c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
