| Reaction Details |
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 | Report a problem with these data |
| Target | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
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| Ligand | BDBM50056954 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1455848 (CHEMBL3362302) |
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| Ki | 1600±n/a nM |
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| Citation |  Amiable, C; Paoletti, J; Haouz, A; Padilla, A; Labesse, G; Kaminski, PA; Pochet, S 6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities. Eur J Med Chem85:418-37 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
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| Name: | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
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| Synonyms: | DNPH1_RAT | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) D69N | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) E93Q | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) S117A | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) Y13F | Dnph1 | Rcl | c-Myc-responsive protein Rcl |
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| Type: | Enzyme |
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| Mol. Mass.: | 17775.23 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | O35820 |
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| Residue: | 163 |
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| Sequence: | MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAG
GDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMI
RGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA
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| BDBM50056954 |
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| n/a |
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| Name | BDBM50056954 |
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| Synonyms: | CHEMBL3331381 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25N4O8P |
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| Mol. Mass. | 564.4832 |
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| SMILES | COc1ccc2cc(ccc2c1)-c1cccc(c1)-c1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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