| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM50058502 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1459580 (CHEMBL3369615) |
|---|
| Ki | 6.7±n/a nM |
|---|
| Citation |  Pinna, G; Curzu, MM; Dore, A; Lazzari, P; Ruiu, S; Pau, A; Murineddu, G; Pinna, GA Tricyclic pyrazoles part 7. Discovery of potent and selective dihydrothienocyclopentapyrazole derived CB2 ligands. Eur J Med Chem85:747-57 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38220.43 |
|---|
| Organism: | MOUSE |
|---|
| Description: | P47936 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
|
|
|
|---|
| BDBM50058502 |
|---|
| n/a |
|---|
| Name | BDBM50058502 |
|---|
| Synonyms: | CHEMBL3331454 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H29Cl2N3OS |
|---|
| Mol. Mass. | 502.499 |
|---|
| SMILES | CC(C)[C@H]1CC[C@H](C)CC1NC(=O)c1nn(c-2c1Cc1scc(C)c-21)-c1ccc(Cl)cc1Cl |r| |
|---|
| Structure | 
|
|---|
Search and Browse
