| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 10 |
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| Ligand | BDBM50340599 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1460661 (CHEMBL3395902) |
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| IC50 | 310±n/a nM |
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| Citation |  Koch, P; Gehringer, M; Laufer, SA Inhibitors of c-Jun N-terminal kinases: an update. J Med Chem58:72-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 10 |
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| Name: | Mitogen-activated protein kinase 10 |
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| Synonyms: | Jnk3 | MK10_RAT | Mapk10 | Prkm10 | c-Jun N-terminal kinase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52534.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1460661 |
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| Residue: | 464 |
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| Sequence: | MSLHFLYYCSEPTLDVKIAFCQGFDKHVDVSSVVKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
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| BDBM50340599 |
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| n/a |
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| Name | BDBM50340599 |
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| Synonyms: | 7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)quinazolin-2-amine | CHEMBL1761554 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23N9O |
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| Mol. Mass. | 453.4991 |
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| SMILES | Cn1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1 |
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| Structure | 
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