| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 10 |
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| Ligand | BDBM50059650 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1460661 (CHEMBL3395902) |
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| IC50 | 3.0±n/a nM |
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| Citation |  Koch, P; Gehringer, M; Laufer, SA Inhibitors of c-Jun N-terminal kinases: an update. J Med Chem58:72-95 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 10 |
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| Name: | Mitogen-activated protein kinase 10 |
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| Synonyms: | Jnk3 | MK10_RAT | Mapk10 | Prkm10 | c-Jun N-terminal kinase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52534.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1460661 |
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| Residue: | 464 |
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| Sequence: | MSLHFLYYCSEPTLDVKIAFCQGFDKHVDVSSVVKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
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| BDBM50059650 |
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| n/a |
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| Name | BDBM50059650 |
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| Synonyms: | CHEMBL3220495 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23ClN6O3 |
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| Mol. Mass. | 454.909 |
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| SMILES | COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2C(N)=O)n1)N1CCOCC1 |
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| Structure | 
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