| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM25769 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1461173 (CHEMBL3395623) |
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| Kd | 245±n/a nM |
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| Citation |  Soriano-Ursúa, MA; Arias-Montaño, JA; Correa-Basurto, J; Hernández-Martínez, CF; López-Cabrera, Y; Castillo-Hernández, MC; Padilla-Martínez, II; Trujillo-Ferrara, JG Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting theß2 adrenoceptor. Bioorg Med Chem Lett25:820-5 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46993.24 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
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| Residue: | 418 |
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| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
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| BDBM25769 |
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| n/a |
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| Name | BDBM25769 |
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| Synonyms: | 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol | Levalbuterol | Proventil | Salbutamol | Salbutamol,(+/-) | albuterol |
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| Type | Small organic molecule |
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| Emp. Form. | C13H21NO3 |
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| Mol. Mass. | 239.3107 |
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| SMILES | CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 |
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| Structure | 
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