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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium-dependent serotonin transporter | ||
| Ligand | BDBM50062224 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1462643 (CHEMBL3399330) | ||
| Ki | 21±n/a nM | ||
| Citation |  Chodkowski, A; Wróbel, MZ; Turlo, J; Kleps, J; Siwek, A; Nowak, G; Belka, M; Baczek, T; Mazurek, AP; Herold, F Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. Part 4. Eur J Med Chem90:21-32 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium-dependent serotonin transporter | |||
| Name: | Sodium-dependent serotonin transporter | ||
| Synonyms: | 5-HT Transporter | 5-HTT | 5HT transporter | 5HTT | Anandamid membrane transporter, AMT | Anandamide membrane transporter, AMT | Monoamine transporters; Norepinephrine & serotonin | SC6A4_RAT | Slc6a4 | Sodium-dependent serotonin transporter | Sodium-dependent serotonin transporter (SERT) | imipramine receptor | ||
| Type: | Multi-pass membrane protein | ||
| Mol. Mass.: | 70168.43 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P31652 | ||
| Residue: | 630 | ||
| Sequence: |
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| BDBM50062224 | |||
| n/a | |||
| Name | BDBM50062224 | ||
| Synonyms: | CHEMBL3397046 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C32H31FN4O3 | ||
| Mol. Mass. | 538.6119 | ||
| SMILES | COc1ccccc1-c1c2ccccn2c(=O)n(CCCCN2CCC(=CC2)c2c[nH]c3ccc(F)cc23)c1=O |c:27,(5.07,3.7,;4,3.08,;2.66,3.85,;2.66,5.39,;1.33,6.16,;-.01,5.39,;-0,3.85,;1.33,3.08,;1.33,1.54,;,.77,;-1.33,1.54,;-2.68,.77,;-2.68,-.77,;-1.33,-1.54,;,-.77,;1.33,-1.54,;1.33,-2.77,;2.66,-.77,;4,-1.54,;5.33,-.76,;6.67,-1.53,;8,-.76,;9.34,-1.53,;9.34,-3.07,;10.67,-3.84,;12,-3.07,;12,-1.53,;10.67,-.76,;13.34,-3.84,;13.48,-5.36,;14.96,-5.67,;15.74,-4.35,;17.26,-4.06,;17.74,-2.57,;16.72,-1.43,;17.11,-.26,;15.19,-1.73,;14.72,-3.2,;2.66,.77,;3.73,1.38,)| | ||
| Structure | 
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