| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50062605 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1462916 (CHEMBL3399856) |
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| IC50 | 540±n/a nM |
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| Citation |  Wu, HQ; Yao, J; He, QQ; Chen, WX; Chen, FE; Pannecouque, C; De Clercq, E; Daelemans, D Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem23:624-31 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50062605 |
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| n/a |
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| Name | BDBM50062605 |
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| Synonyms: | CHEMBL3397645 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16ClN5O2 |
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| Mol. Mass. | 393.826 |
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| SMILES | Cc1cc(OCC(=O)Nc2cccc(Cl)c2)nc(Nc2ccc(cc2)C#N)n1 |
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| Structure | 
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