| Reaction Details |
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 | Report a problem with these data |
| Target | Myeloblastin |
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| Ligand | BDBM166437 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1463425 (CHEMBL3399762) |
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| IC50 | 610±n/a nM |
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| Citation |  Hwang, TL; Wang, WH; Wang, TY; Yu, HP; Hsieh, PW Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3. Bioorg Med Chem23:1123-34 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Myeloblastin |
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| Name: | Myeloblastin |
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| Synonyms: | Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27816.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1463425 |
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| Residue: | 256 |
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| Sequence: | MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
DWIRSTLRRVEAKGRP
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| BDBM166437 |
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| n/a |
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| Name | BDBM166437 |
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| Synonyms: | US9073833, 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O5S |
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| Mol. Mass. | 404.48 |
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| SMILES | CO\N=C(/C)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1 |
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| Structure | 
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