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TargetAmine oxidase [flavin-containing] A
LigandBDBM50110725
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1463343 (CHEMBL3399616)
IC50 3920±n/a nM
Citation Chirkova, ZV; Kabanova, MV; Filimonov, SI; Abramov, IG; Petzer, A; Petzer, JP; Firgang, SI; Suponitsky, KY Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives. Bioorg Med Chem Lett25:1206-11 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] A
Name:Amine oxidase [flavin-containing] A
Synonyms:AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:Protein
Mol. Mass.:59689.53
Organism:Homo sapiens (Human)
Description:P21397
Residue:527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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BDBM50110725
n/a
NameBDBM50110725
Synonyms:5-(hydroxymethyl)-3-(3-methylphenyl)-oxazolidin-2-one | 5-Hydroxymethyl-3-m-tolyl-oxazolidin-2-one | CHEMBL18116 | TOLOXATONE | Taloxotone
TypeSmall organic molecule
Emp. Form.C11H13NO3
Mol. Mass.207.2258
SMILESCc1cccc(c1)N1CC(CO)OC1=O
Structure
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