Reaction Details | |||
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Target | Neurotensin receptor type 1 | ||
Ligand | BDBM50019417 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1466612 (CHEMBL3407205) | ||
Ki | 1210±n/a nM | ||
Citation | Thomas, JB; Giddings, AM; Olepu, S; Wiethe, RW; Warner, KR; Sarret, P; Longpre, JM; Runyon, SP; Gilmour, BP The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2. Bioorg Med Chem Lett25:2060-4 (2015) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neurotensin receptor type 1 | |||
Name: | Neurotensin receptor type 1 | ||
Synonyms: | NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 47070.64 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_1466612 | ||
Residue: | 424 | ||
Sequence: |
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BDBM50019417 | |||
n/a | |||
Name | BDBM50019417 | ||
Synonyms: | CHEMBL3290101 | ||
Type | Small organic molecule | ||
Emp. Form. | C29H29N3O5 | ||
Mol. Mass. | 499.5577 | ||
SMILES | COc1cccc(OC)c1-c1cc(nn1-c1cccc2ccccc12)C(=O)NC1(CCCCC1)C(O)=O |(20.81,-16.86,;21.28,-15.39,;22.79,-15.07,;23.82,-16.21,;25.33,-15.89,;25.8,-14.43,;24.77,-13.29,;25.25,-11.82,;26.75,-11.5,;23.27,-13.61,;21.93,-12.12,;22.25,-10.61,;20.91,-9.84,;19.77,-10.87,;20.39,-12.28,;19.39,-14.01,;20.16,-15.35,;19.39,-16.68,;17.85,-16.68,;17.08,-15.35,;15.54,-15.35,;14.77,-14.01,;15.54,-12.68,;17.08,-12.68,;17.85,-14.01,;20.75,-8.31,;22,-7.41,;19.34,-7.68,;19.18,-6.15,;20.72,-6.26,;21.58,-4.98,;20.91,-3.6,;19.37,-3.49,;18.51,-4.77,;17.69,-6.59,;17.33,-8.07,;16.6,-5.5,)| | ||
Structure |