Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPantothenate kinase 3
LigandBDBM50071455
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1469797
IC50 120±n/a nM
Citation Sharma LKLeonardi RLin WBoyd VAGoktug AShelat AAChen TJackowski SRock CO A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases. J Med Chem 58:1563-8 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pantothenate kinase 3
Name:Pantothenate kinase 3
Synonyms:PANK3 | Pantothenate kinase 3 | Pantothenic acid kinase 3 | hPanK3
Type:PROTEIN
Mol. Mass.:41093.59
Organism:Homo sapiens (Human)
Description:ChEMBL_109587
Residue:370
Sequence:
MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGS
TGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYK
FEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLD
DPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASK
GDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN
IGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAV
GALLGLPNFS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50071455
n/a
NameBDBM50071455
Synonyms:CHEMBL3410245
TypeSmall organic molecule
Emp. Form.C21H23N3O2S
Mol. Mass.381.491
SMILESCC(C)c1ccc(NC(=O)CCc2nc(O)c3c4CCCc4sc3n2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: