| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cell division protein FtsZ |
|---|
| Ligand | BDBM50079361 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1470447 (CHEMBL3418981) |
|---|
| IC50 | 8300±n/a nM |
|---|
| Citation |  Li, X; Ma, S Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ. Eur J Med Chem95:1-15 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cell division protein FtsZ |
|---|
| Name: | Cell division protein FtsZ |
|---|
| Synonyms: | FTSZ_ECOLI | ftsZ | sfiB | sulB |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 40305.83 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P0A9A6 |
|---|
| Residue: | 383 |
|---|
| Sequence: | MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQI
GSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVA
KDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLD
AFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAA
EMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDP
DMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVND
NAPQTAKEPDYLDIPAFLRKQAD
|
|
|
|---|
| BDBM50079361 |
|---|
| n/a |
|---|
| Name | BDBM50079361 |
|---|
| Synonyms: | CHEMBL3416824 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C43H36O8 |
|---|
| Mol. Mass. | 680.7411 |
|---|
| SMILES | Oc1ccccc1Cc1ccc(O)c(Cc2c(O)c(Cc3cc(Cc4ccccc4O)ccc3O)c3O[C@@H](CC(=O)c3c2O)c2ccccc2)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
