| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50083355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1474226 (CHEMBL3424284) |
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| IC50 | 90500±n/a nM |
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| Citation |  Li, X; Sheng, J; Huang, G; Ma, R; Yin, F; Song, D; Zhao, C; Ma, S Design, synthesis and antibacterial activity of cinnamaldehyde derivatives as inhibitors of the bacterial cell division protein FtsZ. Eur J Med Chem97:32-41 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_ECOLI | ftsZ | sfiB | sulB |
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| Type: | Protein |
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| Mol. Mass.: | 40305.83 |
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| Organism: | Escherichia coli |
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| Description: | P0A9A6 |
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| Residue: | 383 |
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| Sequence: | MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQI
GSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVA
KDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLD
AFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAA
EMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDP
DMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVND
NAPQTAKEPDYLDIPAFLRKQAD
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| BDBM50083355 |
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| n/a |
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| Name | BDBM50083355 |
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| Synonyms: | CHEMBL3423282 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12Cl2N2O |
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| Mol. Mass. | 331.196 |
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| SMILES | Cc1nc2ccccc2n1C(=O)\C=C\c1ccc(Cl)cc1Cl |
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| Structure | 
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