| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50083674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1474894 (CHEMBL3423530) |
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| IC50 | 83000±n/a nM |
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| Citation |  Aghazadeh Tabrizi, M; Baraldi, PG; Ruggiero, E; Saponaro, G; Baraldi, S; Romagnoli, R; Martinelli, A; Tuccinardi, T Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH). Eur J Med Chem97:289-305 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50083674 |
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| n/a |
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| Name | BDBM50083674 |
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| Synonyms: | CHEMBL3422944 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26ClN3O4 |
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| Mol. Mass. | 467.945 |
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| SMILES | CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1 |
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| Structure | 
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