| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sodium/nucleoside cotransporter 2 |
|---|
| Ligand | BDBM50085525 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1477251 (CHEMBL3428943) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Tatani, K; Hiratochi, M; Nonaka, Y; Isaji, M; Shuto, S Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett6:244-8 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sodium/nucleoside cotransporter 2 |
|---|
| Name: | Sodium/nucleoside cotransporter 2 |
|---|
| Synonyms: | CNT2 | S28A2_HUMAN | SLC28A2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 71934.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1477251 |
|---|
| Residue: | 658 |
|---|
| Sequence: | MEKASGRQSIALSTVETGTVNPGLELMEKEVEPEGSKRTDAQGHSLGDGLGPSTYQRRSR
WPFSKARSFCKTHASLFKKILLGLLCLAYAAYLLAACILNFQRALALFVITCLVIFVLVH
SFLKKLLGKKLTRCLKPFENSRLRLWTKWVFAGVSLVGLILWLALDTAQRPEQLIPFAGI
CMFILILFACSKHHSAVSWRTVFSGLGLQFVFGILVIRTDLGYTVFQWLGEQVQIFLNYT
VAGSSFVFGDTLVKDVFAFQALPIIIFFGCVVSILYYLGLVQWVVQKVAWFLQITMGTTA
TETLAVAGNIFVGMTEAPLLIRPYLGDMTLSEIHAVMTGGFATISGTVLGAFIAFGVDAS
SLISASVMAAPCALASSKLAYPEVEESKFKSEEGVKLPRGKERNVLEAASNGAVDAIGLA
TNVAANLIAFLAVLAFINAALSWLGELVDIQGLTFQVICSYLLRPMVFMMGVEWTDCPMV
AEMVGIKFFINEFVAYQQLSQYKNKRLSGMEEWIEGEKQWISVRAEIITTFSLCGFANLS
SIGITLGGLTSIVPHRKSDLSKVVVRALFTGACVSLISACMAGILYVPRGAEADCVSFPN
TSFTNRTYETYMCCRGLFQSTSLNGTNPPSFSGPWEDKEFSAMALTNCCGFYNNTVCA
|
|
|
|---|
| BDBM50085525 |
|---|
| n/a |
|---|
| Name | BDBM50085525 |
|---|
| Synonyms: | CHEMBL3427691 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H15N5O5 |
|---|
| Mol. Mass. | 309.278 |
|---|
| SMILES | CC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
