| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium/nucleoside cotransporter 2 |
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| Ligand | BDBM50340678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1477251 (CHEMBL3428943) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Tatani, K; Hiratochi, M; Nonaka, Y; Isaji, M; Shuto, S Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett6:244-8 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium/nucleoside cotransporter 2 |
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| Name: | Sodium/nucleoside cotransporter 2 |
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| Synonyms: | CNT2 | S28A2_HUMAN | SLC28A2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71934.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1477251 |
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| Residue: | 658 |
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| Sequence: | MEKASGRQSIALSTVETGTVNPGLELMEKEVEPEGSKRTDAQGHSLGDGLGPSTYQRRSR
WPFSKARSFCKTHASLFKKILLGLLCLAYAAYLLAACILNFQRALALFVITCLVIFVLVH
SFLKKLLGKKLTRCLKPFENSRLRLWTKWVFAGVSLVGLILWLALDTAQRPEQLIPFAGI
CMFILILFACSKHHSAVSWRTVFSGLGLQFVFGILVIRTDLGYTVFQWLGEQVQIFLNYT
VAGSSFVFGDTLVKDVFAFQALPIIIFFGCVVSILYYLGLVQWVVQKVAWFLQITMGTTA
TETLAVAGNIFVGMTEAPLLIRPYLGDMTLSEIHAVMTGGFATISGTVLGAFIAFGVDAS
SLISASVMAAPCALASSKLAYPEVEESKFKSEEGVKLPRGKERNVLEAASNGAVDAIGLA
TNVAANLIAFLAVLAFINAALSWLGELVDIQGLTFQVICSYLLRPMVFMMGVEWTDCPMV
AEMVGIKFFINEFVAYQQLSQYKNKRLSGMEEWIEGEKQWISVRAEIITTFSLCGFANLS
SIGITLGGLTSIVPHRKSDLSKVVVRALFTGACVSLISACMAGILYVPRGAEADCVSFPN
TSFTNRTYETYMCCRGLFQSTSLNGTNPPSFSGPWEDKEFSAMALTNCCGFYNNTVCA
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| BDBM50340678 |
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| n/a |
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| Name | BDBM50340678 |
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| Synonyms: | 1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluorouracil | 2'-deoxy-5-fluorouridine | 5-Fluoro-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione | 5-Fluoro-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione | 5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | 5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | 5-fluoro-2'-Deoxy-uridine | 5-fluoro-2'-deoxyuridine | CHEMBL917 | FLOXURIDINE | FUDR | Fluoruridine Deoxyribose |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11FN2O5 |
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| Mol. Mass. | 246.1924 |
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| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O |r| |
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| Structure | 
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