| Reaction Details |
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 | Report a problem with these data |
| Target | Receptor-type tyrosine-protein phosphatase R |
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| Ligand | BDBM82577 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1476400 (CHEMBL3430030) |
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| IC50 | 13000±n/a nM |
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| Citation |  Tautz, L; Senis, YA; Oury, C; Rahmouni, S Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy. Bioorg Med Chem23:2786-97 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Receptor-type tyrosine-protein phosphatase R |
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| Name: | Receptor-type tyrosine-protein phosphatase R |
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| Synonyms: | Ch-1PTPase | ECPTP | ECPTP | NC-PTPCOM1 | PTPRQ | PTPRR | PTPRR_HUMAN | Protein-tyrosine phosphatase PCPTP1 | R-PTP-R | Receptor-type tyrosine-protein phosphatase R |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73850.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109611 |
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| Residue: | 657 |
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| Sequence: | MRRAVCFPALCLLLNLHAAGCFSGNNDHFLAINQKKSGKPVFIYKHSQDIEKSLDIAPQK
IYRHSYHSSSEAQVSKRHQIVNSAFPRPAYDPSLNLLAMDGQDLEVENLPIPAANVIVVT
LQMDVNKLNITLLRIFRQGVAAALGLLPQQVHINRLIGKKNSIELFVSPINRKTGISDAL
PSEEVLRSLNINVLHQSLSQFGITEVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFVI
IVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLN
VVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIP
TPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNR
YKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMV
WQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSH
TQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIA
TSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ
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| BDBM82577 |
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| n/a |
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| Name | BDBM82577 |
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| Synonyms: | (4-fluoro-1,3-benzothiazol-2-yl)-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]amine | MLS-0437605.0002 | N-(4-fluoranyl-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine | N-(4-fluoro-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine | cid_7158830 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11FN4O2S |
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| Mol. Mass. | 342.348 |
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| SMILES | COc1ccc(cc1)-c1nnc(Nc2nc3c(F)cccc3s2)o1 |
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| Structure | 
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