| Reaction Details |
|---|
 | Report a problem with these data |
| Target | M-phase inducer phosphatase 2 |
|---|
| Ligand | BDBM50088048 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1476528 (CHEMBL3428079) |
|---|
| IC50 | 10800±n/a nM |
|---|
| Citation |  Carneiro, VM; Trivella, DB; Scorsato, V; Beraldo, VL; Dias, MP; Sobreira, TJ; Aparicio, R; Pilli, RA Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues. Eur J Med Chem97:42-54 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| M-phase inducer phosphatase 2 |
|---|
| Name: | M-phase inducer phosphatase 2 |
|---|
| Synonyms: | CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 64985.27 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 580 |
|---|
| Sequence: | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
|
|
|
|---|
| BDBM50088048 |
|---|
| n/a |
|---|
| Name | BDBM50088048 |
|---|
| Synonyms: | CHEMBL3427125 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H38O6 |
|---|
| Mol. Mass. | 410.5442 |
|---|
| SMILES | CCCCCCCCCCCCCCCC(=O)C1=C(O)C(COC(C)=O)OC1=O |c:17| |
|---|
| Structure | 
|
|---|
Search and Browse
