| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1A2 |
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| Ligand | BDBM50448435 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1487340 (CHEMBL3535132) |
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| Ki | 13600±n/a nM |
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| Citation |  Wattanachai, N; Tassaneeyakul, W; Rowland, A; Elliot, DJ; Bowalgaha, K; Knights, KM; Miners, JO Effect of albumin on human liver microsomal and recombinant CYP1A2 activities: impact on in vitro-in vivo extrapolation of drug clearance. Drug Metab Dispos40:982-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1A2 |
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| Name: | Cytochrome P450 1A2 |
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| Synonyms: | CP1A2_RAT | CYPIA2 | Cyp1a-2 | Cyp1a2 | Cytochrome P-448 | Cytochrome P-450d | Cytochrome P450-D |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58273.18 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1487340 |
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| Residue: | 513 |
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| Sequence: | MAFSQYISLAPELLLATAIFCLVFWVLRGTRTQVPKGLKSPPGPWGLPFIGHMLTLGKNP
HLSLTKLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVKQGDDFKGRPDLYSFTLITNGK
SMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSVSSCYLEEHVSKEANHLISKFQKLMA
EVGHFEPVNQVVESVANVIGAMCFGKNFPRKSEEMLNLVKSSKDFVENVTSGNAVDFFPV
LRYLPNPALKRFKNFNDNFVLFLQKTVQEHYQDFNKNSIQDITGALFKHSENYKDNGGLI
PQEKIVNIVNDIFGAGFETVTTAIFWSILLLVTEPKVQRKIHEELDTVIGRDRQPRLSDR
PQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKECCIFINQWQVNHDEKQWK
DPFVFRPERFLTNDNTAIDKTLSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLHQLEFT
VPPGVKVDLTPSYGLTMKPRTCEHVQAWPRFSK
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| BDBM50448435 |
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| n/a |
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| Name | BDBM50448435 |
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| Synonyms: | CHEMBL3122088 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H31O2 |
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| Mol. Mass. | 279.4381 |
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| SMILES | CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O |
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| Structure | 
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