| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arylacetamide deacetylase |
|---|
| Ligand | BDBM50131270 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1481892 (CHEMBL3540583) |
|---|
| Ki | 14000±n/a nM |
|---|
| Citation |  Kobayashi, Y; Fukami, T; Nakajima, A; Watanabe, A; Nakajima, M; Yokoi, T Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse. Drug Metab Dispos40:671-9 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arylacetamide deacetylase |
|---|
| Name: | Arylacetamide deacetylase |
|---|
| Synonyms: | AAAD_HUMAN | AADAC | Arylacetamide deacetylase | DAC |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45743.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_109673 |
|---|
| Residue: | 399 |
|---|
| Sequence: | MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMD
SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSA
ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNP
ERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLF
LSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP
NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTG
VQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL
|
|
|
|---|
| BDBM50131270 |
|---|
| n/a |
|---|
| Name | BDBM50131270 |
|---|
| Synonyms: | 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide | 4'-nitro-3'-trifluoromethylisobutyranilide | CHEMBL806 | Eulexin | FLUTAMIDE | Niftolide | alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide | niftolid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H11F3N2O3 |
|---|
| Mol. Mass. | 276.2118 |
|---|
| SMILES | CC(C)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
