| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucuronosyltransferase 1A8 |
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| Ligand | BDBM50044561 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1492337 (CHEMBL3527918) |
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| Ki | 3640±n/a nM |
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| Citation |  Uchihashi, S; Fukumoto, H; Onoda, M; Hayakawa, H; Ikushiro, S; Sakaki, T Metabolism of the c-Fos/activator protein-1 inhibitor T-5224 by multiple human UDP-glucuronosyltransferase isoforms. Drug Metab Dispos39:803-13 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucuronosyltransferase 1A8 |
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| Name: | UDP-glucuronosyltransferase 1A8 |
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| Synonyms: | GNT1 | GNT1 | UD18_HUMAN | UDP-glucuronosyltransferase 1-8 | UDP-glucuronosyltransferase 1-H | UDP-glucuronosyltransferase 1A8 | UDPGT 1-8 | UGT-1H | UGT1 | UGT1*8 | UGT1-08 | UGT1.8 | UGT1A8 | UGT1H |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59751.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104086 |
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| Residue: | 530 |
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| Sequence: | MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP
EVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLF
FSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEG
AQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVT
AYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV
VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH
PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL
ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
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| BDBM50044561 |
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| n/a |
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| Name | BDBM50044561 |
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| Synonyms: | CHEMBL3222137 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H27NO8 |
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| Mol. Mass. | 517.5266 |
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| SMILES | OC(=O)CCc1cc(ccc1OCc1ccc2c(O)noc2c1)C(=O)c1ccc(OC2CCCC2)cc1O |
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| Structure | 
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