| Reaction Details |
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 | Report a problem with these data |
| Target | Urotensin-2 receptor |
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| Ligand | BDBM50089660 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1496205 (CHEMBL3579089) |
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| EC50 | 1.5±n/a nM |
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| Citation |  Dufour-Gallant, J; Chatenet, D; Lubell, WD De Novo Conception of Small Molecule Modulators Based on Endogenous Peptide Ligands: Pyrrolodiazepin-2-oneż-Turn Mimics That Differentially Modulate Urotensin II Receptor-Mediated Vasoconstriction ex Vivo. J Med Chem58:4624-37 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urotensin-2 receptor |
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| Name: | Urotensin-2 receptor |
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| Synonyms: | G-protein coupled receptor 14 | G-protein coupled sensory epithelial neuropeptide-like receptor | Gpr14 | Senr | UR-II-R | UR2R_RAT | Urotensin-II | Uts2r |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42725.34 |
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| Organism: | RAT |
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| Description: | Urotensin-II UTS2R RAT::P49684 |
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| Residue: | 386 |
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| Sequence: | MALSLESTTSFHMLTVSGSTVTELPGDSNVSLNSSWSGPTDPSSLKDLVATGVIGAVLSA
MGVVGMVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIIATYVTKDWHFGD
VGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLVLGTWLLALLL
TLPMMLAIQLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYVRLARAYWL
SQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHEAMPLTPETARIVNY
LTTCLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCHSPGSPGSFLPSRVHLQQDSG
RSLSSSSQQATETLMLSPVPRNGALL
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| BDBM50089660 |
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| n/a |
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| Name | BDBM50089660 |
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| Synonyms: | CHEMBL3577311 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H32N4O4 |
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| Mol. Mass. | 512.5995 |
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| SMILES | NCCCC[C@@H]1N[C@H](c2[nH]c(cc2N(CCc2ccc(O)cc2)C1=O)C(O)=O)c1ccc2ccccc2c1 |r| |
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| Structure | 
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