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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Glucocorticoid receptor | ||
| Ligand | BDBM50091046 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1499884 (CHEMBL3583216) | ||
| Ki | 15±n/a nM | ||
| Citation |  Eda, M; Kuroda, T; Kaneko, S; Aoki, Y; Yamashita, M; Okumura, C; Ikeda, Y; Ohbora, T; Sakaue, M; Koyama, N; Aritomo, K Synthesis and Biological Evaluation of Cyclopentaquinoline Derivatives as Nonsteroidal Glucocorticoid Receptor Antagonists. J Med Chem58:4918-26 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Glucocorticoid receptor | |||
| Name: | Glucocorticoid receptor | ||
| Synonyms: | GCR_HUMAN | GR | GRL | Glucocorticoid | Glucocorticoid receptor (GRFP) | NR3C1 | Nuclear receptor subfamily 3 group C member 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 85656.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P04150 | ||
| Residue: | 777 | ||
| Sequence: |
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| BDBM50091046 | |||
| n/a | |||
| Name | BDBM50091046 | ||
| Synonyms: | CHEMBL3582112 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H26N2O2 | ||
| Mol. Mass. | 338.4433 | ||
| SMILES | Cc1noc(C)c1-c1cc2c(NC(C)(C)C(=O)C2(C)C)c2CCCc12 |(2.54,-4.54,;3.47,-3.72,;4.98,-4.05,;5.76,-2.71,;4.73,-1.56,;4.98,-.35,;3.33,-2.19,;2.01,-1.4,;.66,-2.12,;-.68,-1.4,;-.68,.15,;-2.01,.93,;-3.37,.15,;-4.42,-.49,;-3.33,1.39,;-3.37,-1.4,;-4.43,-2.04,;-2.01,-2.12,;-.91,-2.7,;-3.09,-2.71,;.66,.93,;.98,2.44,;2.53,2.61,;3.18,1.19,;2.01,.15,)| | ||
| Structure | 
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