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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bromodomain-containing protein 3 | ||
| Ligand | BDBM50092311 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1498014 (CHEMBL3585075) | ||
| Ki | 10±n/a nM | ||
| Citation |  Ran, X; Zhao, Y; Liu, L; Bai, L; Yang, CY; Zhou, B; Meagher, JL; Chinnaswamy, K; Stuckey, JA; Wang, S Structure-Based Design of¿-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors. J Med Chem58:4927-39 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bromodomain-containing protein 3 | |||
| Name: | Bromodomain-containing protein 3 | ||
| Synonyms: | BRD3 | BRD3_HUMAN | Bromodomain and extra-terminal motif (BET) | Bromodomain-containing protein 3 | Bromodomain-containing protein 3 (BRD3) | KIAA0043 | RING3-like protein | RING3L | ||
| Type: | Protein | ||
| Mol. Mass.: | 79571.81 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15059 | ||
| Residue: | 726 | ||
| Sequence: |
| ||
| BDBM50092311 | |||
| n/a | |||
| Name | BDBM50092311 | ||
| Synonyms: | CHEMBL3581662 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H25N5O2 | ||
| Mol. Mass. | 463.5304 | ||
| SMILES | CCc1[nH]nc(c1-c1nccc2[nH]c3cc(-c4c(C)noc4C)c(OC)cc3c12)-c1ccccc1 |(1.05,4.4,;.13,3.57,;-1.35,4.05,;-1.84,5.52,;-3.39,5.51,;-3.86,4.03,;-2.59,3.15,;-2.58,1.59,;-3.83,.85,;-3.83,-.63,;-2.58,-1.37,;-1.27,-.63,;,-1.37,;1.27,-.63,;2.56,-1.37,;3.87,-.63,;5.21,-1.41,;5.36,-2.94,;4.43,-3.77,;6.87,-3.26,;7.65,-1.92,;6.61,-.77,;6.86,.45,;3.87,.85,;5.21,1.63,;5.21,2.88,;2.56,1.59,;1.27,.85,;-1.27,.85,;-5.33,3.53,;-5.75,2.04,;-7.25,1.66,;-8.34,2.77,;-7.92,4.26,;-6.41,4.65,)| | ||
| Structure | 
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