| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleophosmin |
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| Ligand | BDBM50094238 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1502715 (CHEMBL3590711) |
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| EC50 | 2500±n/a nM |
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| Citation |  Penthala, NR; Crooks, PA; Freeman, ML; Sekhar, KR Development and validation of a novel assay to identify radiosensitizers that target nucleophosmin 1. Bioorg Med Chem23:3681-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nucleophosmin |
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| Name: | Nucleophosmin |
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| Synonyms: | NPM | NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor) | NPM1 | NPM_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32552.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502715 |
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| Residue: | 294 |
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| Sequence: | MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG
PSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
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| BDBM50094238 |
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| n/a |
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| Name | BDBM50094238 |
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| Synonyms: | CHEMBL3589689 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16BrN3O2S |
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| Mol. Mass. | 454.34 |
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| SMILES | [#6]-c1c(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)c2ccccc2n1-[#6]-c1ccc(Br)cc1 |
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| Structure | 
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