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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 1A | ||
| Ligand | BDBM50274835 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1505669 (CHEMBL3594589) | ||
| Ki | 0.028000±n/a nM | ||
| Citation |  Stroth, N; Niso, M; Colabufo, NA; Perrone, R; Svenningsson, P; Lacivita, E; Leopoldo, M Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of฿-arrestin-2. Bioorg Med Chem23:4824-30 (2015) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 1A | |||
| Name: | 5-hydroxytryptamine receptor 1A | ||
| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A | ||
| Type: | n/a | ||
| Mol. Mass.: | 46122.49 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 422 | ||
| Sequence: |
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| BDBM50274835 | |||
| n/a | |||
| Name | BDBM50274835 | ||
| Synonyms: | CHEMBL511857 | trans-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(pyridin-2-yl)piperazine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H29N3O | ||
| Mol. Mass. | 351.4852 | ||
| SMILES | COc1cccc(c1)[C@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:8.8,wD:11.15,(1.87,-39.15,;3.2,-38.38,;3.2,-36.84,;1.87,-36.07,;1.87,-34.53,;3.2,-33.76,;4.53,-34.52,;4.54,-36.07,;5.86,-33.74,;5.85,-32.21,;7.19,-31.43,;8.53,-32.2,;8.52,-33.74,;7.2,-34.51,;9.85,-31.43,;11.19,-32.21,;12.52,-31.44,;12.52,-29.9,;11.19,-29.13,;9.85,-29.9,;13.86,-29.14,;13.86,-27.61,;15.19,-26.84,;16.53,-27.61,;16.52,-29.15,;15.19,-29.92,)| | ||
| Structure | 
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