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TargetLow molecular weight phosphotyrosine protein phosphatase
LigandBDBM50096252
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1506094 (CHEMBL3595960)
Ki 47000±n/a nM
Citation Fonseca, EMTrivella, DBScorsato, VDias, MPBazzo, NLMandapati, KRde Oliveira, FLFerreira-Halder, CVPilli, RAMiranda, PCAparicio, R Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. Bioorg Med Chem23:4462-71 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Low molecular weight phosphotyrosine protein phosphatase
Name:Low molecular weight phosphotyrosine protein phosphatase
Synonyms:Acp1 | LMW-PTP | LMW-PTPase | Low molecular weight cytosolic acid phosphatase | Low molecular weight phosphotyrosine protein phosphatase | PPAC_MOUSE
Type:PROTEIN
Mol. Mass.:18192.04
Organism:Mus musculus
Description:ChEMBL_109834
Residue:158
Sequence:
MAEVGSKSVLFVCLGNICRSPIAEAVFRKLVTDEKVSDNWRIDSAATSTYEVGNPPDYRG
QNCMRKHGIHMQHIARQITKEDFATFDYILCMDESNLRDLNRKSNQVKNCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFEVVYQQCLRCCKAFLEKTY
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BDBM50096252
n/a
NameBDBM50096252
Synonyms:CHEMBL3594198
TypeSmall organic molecule
Emp. Form.C8H10ClO3P
Mol. Mass.220.59
SMILESOP(O)(=O)Cc1ccc(CCl)cc1
Structure
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